You are not conducting original research; you will only be developing a proposal for future research. You identified a model to promote EBP clinical research on Narcolepsy & Cataplexy. Please use model to organize your final proposal. In addition, integrate the Part 1 PICO(T) paper, Part 2 Literature review and this Part 3 to synthesize your findings and draw conclusions. Include in Part 3 how you might apply for funding for this project. Please use the Proposal paper outline provided for you during the first week as a guide for your paper. 

This assignment requires proper APA format. This includes a title page, reference page, and proper headings. An abstract is required for this final proposal.   The Final EBPG proposal requires 7 pages in addition to the title page, abstract page, and reference page.

Running Head: CLINICAL EVIDENCE BASED PRACTICE 1

CLINICAL EVIDENCE BASED PRACTICE 5

Narcolepsy with Cataplexy

Nicole Stallworth

Herzing University

Clinical Evidence Based Practice.

  Narcolepsy with cataplexy is a sleep disorder that affects about 0.02% of adults in the world. The disorder is characterized by sleepiness during the daytime, with loss of muscle tone. Narcolepsy on its own is a sleep disorder in which there is excessive sleepiness and hallucinations. The disorder occurs in men with an equal chance of occurrence in women. Symptoms of the disease appear in childhood or during adolescence. Most people who have the symptoms of the disorder go for years without getting an appropriate diagnosis. People with the disorder have an urge to sleep even during normal activities. Sleep characteristics can even occur while a person is awake. In cataplexy, there is muscle paralysis of the Rapid Eye Movement (REM) phase of the sleep cycle, which occurs during waking hours. It results in loss of muscle tone, leading to weakness of the trunk, arms and legs. The main cause of narcolepsy with cataplexy is deficiency of hypocretin, a hormone from the brain. The hormone alerts systems in the brain, regulating sleep wake cycles. In the condition, the cells that produce hypocretin, which are located in the hypothalamus, are destroyed. There is no cure for the condition at the moment. However, behavioural treatments and some medications can help improve symptoms in patients. When well managed, patients lead normal lives (Dauvilliers et al, 2007). The topic is important in nursing care due to the several cases of misdiagnosis of the condition taking place. Notably, the condition can be diagnosed through physical examinations, medical history taking and conducting sleep studies on patients. Based on the nature of diagnosing the condition, nurses are best suited to diagnose the problem, as they care for the patient (Rios et al, 2010).

For a nurse to obtain relevant yet sensitive information from a patient, which can guide them to diagnosing a problem such as narcolepsy with cataplexy, there is need for a model to guide in assessing the patient. The PICOT question format is a formula for developing researchable and answerable questions, which clinicians can use to ease the evaluation process. Notably, most nurses fail to understand the real cause of conditions facing a patient apart from the disease itself, due to lack of the skills necessary in assessment. They also do not understand that in clinical care, there is need to focus on a multi-sectorial approach in order to understand what really intensifies the condi

Running Head: NARCOLEPSY AND CATAPLEXY

NARCOLEPSY AND CARTAPLEXY 6


Study of Narcolepsy and cataplexy

Nicole Stallworth

Herzing University

Study of Narcolepsy and cataplexy

Narcolepsy

Narcolepsy is a serious cause of chronic sleeplessness. It normally develop in teen period and usually develop for life. It can be described as neurological syndrome that leads to sleepless and other symptoms that come along are short episode of the muscle failure or weakness, dreamlike hallucinations, a short period or episode f paralysis that’s when one is waking up or falling asleep them lastly there is a disjointed nighttime sleep. The disease and its symptoms usually begins at the age of10 to 20 (Schwartz, 2017). However, in other cases it starts late. Both men and women are affected at the same rate. It approximately affects 1 person out of 2,000 people. It’s a disease that is manageable. The following are types of narcolepsy, narcolepsy with cataplexy and then narcolepsy without cataplexy. The only difference is people who has narcolepsy without cataplexy are affected with sleeplessness. However, faces no muscle weakness. They don’t face severe signs. This are the two types that are today recognized by clinicians. Another rare cases arise with the injury to the hypothalamus, this is usually called secondary narcolepsy.

Causes Narcolepsy

The exact cause of narcolepsy, but researchers and scientist has identified genes that are associated with the condition. This type of gene are specifically in control of the production or yield of the chemicals founded in brain that signals sleep or awake routine or cycles. In other discussion some scientists argue that narcolepsy comes with the deficiency in secretion of the chemical hypocretin in the brain (Schwartz, 2017). In other cases some feel that it due to abnormalities in certain parts of the brain that regulate REM sleep. Then as a result these abnormalities influence the development of those symptoms. Experts feels that narcolepsy is enhanced by varied factors that comes together or relate to cause neurological disorder.

Symptoms of Narcolepsy

Excessive daytime sleepiness, this in many cases interrupt the normal happenings on a regular basis. Most people who suffers from narcolepsy has reported, memory lapse, depressed moods, mental cloudiness, and lastly lack of concentration and also energy. Cataplexy, loss of muscle tone that makes one too weak and also reduced muscle control. Certain part are interfered with such as speech and o can collapse at a given chance. It perhaps depend on the type of muscle as most of the time t